Analytical Chemist

3d3 days ago

Guidehouse

Bethesda, US · Full-time · $98,000 – $163,000

About this role

We are currently searching for an Analytical Chemist to provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute (NHLBI). This is a full-time, on-site opportunity in Bethesda, MD.

Operate, maintain, calibrate, and troubleshoot analytical instrumentation including HPLC, GC, LC/MS, TLC scanners, balances, and water purification systems. Perform quality control testing of PET drug products, raw materials, reagents, and reference standards using chromatography and spectroscopy techniques.

Ensure compliance with laboratory standard operations procedures (SOPs), documentation practices, and regulatory requirements. Coordinate QC testing schedules to support time-sensitive PET radiopharmaceutical production. Train laboratory personnel on QC procedures, equipment operation, and safety protocols while adhering to NIH laboratory safety and radiation safety guidelines.

Develop, optimize, validate, and troubleshoot analytical methods and QC procedures. Perform simple chemical reactions, purification procedures, and compound characterization using established protocols. Maintain laboratory inventories, supplies, reagents, and documentation systems while supporting routine operations and continuous process improvements.

Requirements

PhD in Analytical Chemistry, Chemistry, Pharmaceutical Sciences, Radiochemistry, or related fields with at least two years of experience, OR Master's degree in a related field with at least four years of experience.
Strong knowledge of analytical chemistry principles and techniques.
Experience operating analytical instrumentation such as HPLC, GC, LC/MS, and related systems.
Ability to obtain Public Trust clearance.
Experience with PET radiopharmaceutical quality control and testing methodologies.
Knowledge of laboratory safety and radiation safety guidelines.

Responsibilities

Operate, maintain, calibrate, and troubleshoot analytical instrumentation including HPLC, GC, LC/MS, TLC scanners, balances, and water purification systems.
Perform quality control (QC) testing of PET drug products, raw materials, reagents, and reference standards.
Conduct analytical testing using chromatography and spectroscopy techniques including HPLC, TLC, GC, UV-VIS, and mass spectrometry.
Develop, optimize, validate, and troubleshoot analytical methods and QC procedures.
Ensure compliance with laboratory standard operations procedures (SOPs), documentation practices, and regulatory requirements.
Coordinate QC testing schedules to support time-sensitive PET radiopharmaceutical production.
Train laboratory personnel on QC procedures, equipment operation, and safety protocols.
Perform simple chemical reactions, purification procedures, and compound characterization using established protocols.