Senior Scientist I - Analytical Chemistry

2d2 days ago

AbbVie

North Chicago, US · Full-time · $110,000 – $140,000

About this role

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address medical challenges of tomorrow. This role focuses on the analytical aspects of peptide product development within key therapeutic areas.

You will lead control strategy development, specification justification, method development and validation, and data generation for regulatory submissions. Proficiency in advanced analytical techniques such as mass spectrometry, amino acid analysis, and separation methods is essential for supporting peptide active pharmaceutical ingredients and intermediates.

Operating with high autonomy, you will design follow-on experiments from multidisciplinary data and initiate new investigations that can be incorporated directly into development programs. Cross-functional collaboration with interdisciplinary scientists and engineers is a routine part of the role.

This position offers the opportunity to drive scientific initiative and creativity while maintaining a high level of productivity in the lab. Your contributions will directly impact AbbVie's pipeline in immunology, oncology, neuroscience, and aesthetics.

Requirements

Bachelors, Masters, or Ph.D. in Analytical Chemistry with 10 to 12 (BS), 8 to 10 (MS), or 0 to 4 (Ph.D.) years of peptide-related industry experience.
Strong technical background in analytical chemistry with excellent analytical problem-solving skills.
Ability to independently develop and troubleshoot analytical methods.
Experience in analytical techniques relevant to peptide product development including mass spectrometry, amino acid analysis, advanced separation techniques, and higher-order structure studies.
Familiarity with forced degradation, impurity tracking, and stability requirements for peptide products.
Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
Preferred: Advanced degree in Analytical Chemistry; understanding of cGMP and regulatory requirements; practical knowledge of modern peptide manufacturing processes, organic structure, functional groups, and chemistry.

Responsibilities

Lead the analytical aspects of a project including control strategy development, specification justification, method development and validation, data generation, and regulatory submission contributions.
Apply proficiency in relevant analytical techniques to support development of peptide products, including active pharmaceutical ingredient, intermediates, starting materials, and impurity profiling.
Support new product development with advanced methods development and validations, technical transfer packages, and generation of technical data to meet regulatory requirements.
Perform laboratory research and method development independently with minimal supervision, formulating conclusions and designing follow-on experiments based on multidisciplinary data.
Process, interpret, and visualize data to facilitate project team decisions.
Communicate and collaborate with cross-functional groups and departments.
Routinely demonstrate scientific initiative and creativity in research or development activities while maintaining high productivity in the lab.
Adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, and GxP compliance where applicable.