Manager / Principal Scientist - Polymer Formulation

5d5 days ago

Cresilon, Inc.

Brooklyn, US · Full-time · $130,000 – $180,000

About this role

Cresilon is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company’s proprietary hydrogel technology. The R&D Manager / Principal Scientist - Polymer Formulation will lead the design, development, and implementation of novel formulations and polymer materials for use in medical devices.

This role provides technical leadership and expertise in materials formulation development while building and optimizing internal capabilities to deliver innovative medical device and combination product solutions. Key responsibilities include developing and characterizing polymer material formulation solutions, managing technical collaborations with external suppliers, and integrating formulation solutions into scalable manufacturing processes.

This is a senior technical role overseeing a small team within a dynamic, growing organization. The R&D Manager / Principal Scientist is both a strategic leader and a hands-on contributor, expected to remain actively engaged in laboratory work, directly contributing to experimental design, execution, troubleshooting, and data interpretation.

The role requires a player-coach mindset, with the ability to balance people leadership, technical oversight, and individual scientific contribution. The individual will work at multiple levels—from setting technical direction to performing bench-scale formulation development and characterization activities as needed to meet program timelines.

Requirements

Subject matter expertise in polymer materials science, formulation strategies, analytical chemistry, and biomaterial interactions with biological systems.
Proven ability to lead and manage a small team in a dynamic, cross-functional environment.
Hands-on experience in bench-scale formulation development and characterization.
Strong scientific rigor and ability to uphold high standards in research practices.
Experience supporting technology transfer into manufacturing environments.
Ability to balance strategic leadership with individual scientific contribution.
Flexibility and strong drive to explore and implement new technologies.

Responsibilities

Lead, staff, and manage formulation development teams and their efforts across multiple parallel product development opportunities to launch new commercially successful products.
Provide sound scientific leadership, monitoring, and coaching through the initiation, planning, and execution of their team’s overall activities.
Create and lead experimentation of exploratory and/or product development research to advance the company’s pipeline.
Develop and characterize polymer material formulation solutions for medical devices.
Manage technical collaborations with external suppliers and vendors.
Integrate formulation solutions into scalable manufacturing processes, whether in-house or through CDMOs.
Lead the development of documentation required for regulatory submissions (e.g., 510(k), IDE, technical files).
Drive strategy for publications and grant applications, securing non-dilutive funding through grant opportunities.

Benefits

Opportunity to work on life-saving hemostatic medical devices using proprietary hydrogel technology.
Senior technical leadership role with both strategic and hands-on responsibilities.
Work in a highly collaborative, cross-functional environment.
Full-time, on-site position located in Brooklyn, New York.