Senior / Process Development Chemist

22h22 hours ago

GSK

Singapore, SG · Full-time · S$120,000 – S$180,000

About this role

We are seeking a highly motivated and experienced Senior / Process Development Chemist to join the Jurong Pilot Plant (JPP). In this role, you will oversee the Rapid API system and chemistry laboratory functions, enabling the seamless introduction of new processes from R&D into pilot-scale production. You will support the manufacture of drug substances for clinical, toxicology, and safety trials.

You will evaluate commercial-scale feasibility, identify scale-up challenges, and drive design-for-manufacture (DFM) opportunities. This includes supporting technical transfers from R&D into manufacturing and commissioning new laboratory equipment to strengthen site capabilities. Rapid API is a next-generation robotic and programmable platform that automates end-to-end chemical processing.

Partner with R&D project teams to translate process development objectives into laboratory-scale studies. Collaborate with Pilot Plant teams to establish recipes, equipment configurations, and analytical methods. Conduct laboratory experiments using manual setups and automated Rapid API workflows.

Drive continuous improvement and expansion of Rapid API capabilities to cover additional unit operations. Act as a champion for digital and smart manufacturing technologies, promoting Rapid API adoption. Manage laboratory equipment while ensuring compliance with EHS and GMP standards.

Requirements

Bachelor’s degree in Science or Engineering, with a minimum of 5 years of pharmaceutical or laboratory experience
Strong knowledge of manufacturing requirements for optimum process operations
PhD or MSc in Synthetic Organic Chemistry
Hands-on experience with programmable laboratory or automated systems
Experience in running and interpreting DoE studies
Knowledge of programming, coding, or automation workflows
Strong communication skills and ability to work effectively in cross-functional teams

Responsibilities

Partner with R&D project teams to translate process development objectives into laboratory-scale studies
Design and evaluate process routes, determine scale of operation, and define appropriate equipment and workflows
Plan material requirements and coordinate logistics for laboratory and pilot studies
Collaborate with Pilot Plant teams to establish recipes, equipment configurations, and analytical methods
Conduct laboratory experiments using both manual setups and automated Rapid API workflows
Develop, program, and execute workflow recipes on the Rapid API platform
Perform reaction monitoring, sample analysis, and compile results into technical reports
Conduct robustness, kinetics, and scale-up studies to validate process feasibility