About this role
LGC Axolabs is a leading provider of CRO/CDMO capability to the therapeutic oligonucleotide discovery and development industry. The Petaluma facility focuses on manufacturing scale-up and production to cGMP of multigram to kilograms of API for pre-clinical and clinical development. Join our newly commissioned state-of-the-art therapeutic oligonucleotide GMP manufacturing facility in Petaluma, CA.
Work in a Process Development lab to develop, transfer, and trouble-shoot processes for smooth transfer to GMP and non-GMP manufacturing. Collaborate closely with analytical and production chemists to solve manufacturing issues. This role supports discovery, pre-clinical, clinical trials, and scale-up manufacture.
With around 70 staff and two manufacturing trains, Axolabs offers flexible manufacturing services drawing on expertise from our Kulmbach site. Our California site has been involved in oligonucleotide synthesis for three decades, establishing therapeutics activity in 2019. Benefit from deep knowledge in Nucleic Acid Therapeutics tracing back over 20 years.
Work collaboratively and responsively with clients to achieve objectives using bioinformatics, biology, chemistry, manufacturing, and analytical services. Gain exposure to a broad suite of services in a dynamic environment. Contribute to lead candidate identification and development in a high-expertise team.
Requirements
- Bachelor’s degree required, master’s preferred in Chemistry, Chemical Engineering, or related discipline
- Minimum 1 year of practical experience working in an organic or bioprocess laboratory
- Experience working with TFF, preparative HPLC, UV and pH equipment desired
- Advanced proficiency with Microsoft Outlook, Word, and Excel (Macro)
- Experience with chromatography and/or oligo synthesis system software preferred
- Proficiency in use of a web browser
Responsibilities
- Develop processes in Process Development lab for therapeutic oligonucleotide manufacturing
- Transfer processes to GMP and non-GMP manufacturing
- Trouble-shoot processes for smooth manufacturing transfer
- Collaborate with analytical chemists to solve manufacturing issues
- Collaborate with production chemists to address production challenges
- Support scale-up from multigram to kilogram API production
- Assist in pre-clinical and clinical development manufacturing
Benefits
- Comprehensive medical, dental, and vision benefits for employees and dependents
- FSA/HSA Pre-tax savings plans for health care, childcare, and elder care
- 401(k) retirement plan with matching employer contribution
- Company-paid short- and long-term disability, life insurance, and employee assistance program
- Flexible work options
- Enhanced Parental leave of 8 additional weeks
- PTO that begins immediately
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