Process Development Chemist II

21h21 hours ago

LGC Group

Petaluma, US · Full-time · $69,000 – $115,000

About this role

LGC Axolabs, a business unit of LGC, provides CRO/CDMO services for therapeutic oligonucleotide discovery and development. The Petaluma facility focuses on cGMP manufacturing scale-up of multigram to kilogram API quantities. Join as Process Development Chemist II to develop and optimize processes supporting pre-clinical and clinical trials.

Work in an innovative lab to transfer processes and troubleshoot production issues for new projects. Ensure flawless execution in therapeutic oligonucleotide manufacturing. Operating Monday-Thursday from 8:00am-6:00pm PST supports work-life balance.

Collaborate with an ambitious team of around 70 staff using two manufacturing trains. Draw on deep expertise from Kulmbach site with over 20 years in nucleic acid therapeutics. Provide flexible manufacturing services with chemistry and analytical support.

Contribute to scale-up production drawing on three decades of oligonucleotide synthesis experience. Optimize methods for handover to routine manufacturing. Advance capabilities in solid-phase synthesis, purification, and downstream processing.

Requirements

Minimum 2 years practical experience in organic or bioprocess laboratory
Bachelor’s degree in chemistry, Chemical Engineering, or related field
Proficiency working with HPLC, UV, and pH equipment
Proven ability to provide technical support in root cause failure analysis
Outstanding record-keeping of production activities and analytical data
Ability to maintain laboratory space in compliance with safety regulations
Experience providing technical customer support and progress updates
Self-motivated with ability to work independently and collaboratively

Responsibilities

Develop and optimize processes to support therapeutic oligonucleotide manufacturing
Transfer processes and troubleshoot production issues ensuring flawless execution
Provide technical support in root cause failure analysis for production incidents
Operate HPLC, UV, and pH equipment for analytical support
Maintain detailed records of production activities, experimental procedures, and data
Ensure chemistry laboratory complies with safety regulations
Deliver technical customer support and routine progress updates to clients
Optimize solid-phase oligonucleotide synthesis, purification, and downstream processing