Senior Scientist - Medicinal Chemistry

About this role

Requirements

• Doctorate degree OR Master’s degree and 3 years of laboratory experience OR Bachelor’s degree and 5 years of laboratory experience
• Doctorate degree in chemistry specializing in organic synthesis
• 2+ years of experience in synthetic organic or medicinal chemistry
• Consistent track record of academic accomplishments (e.g., peer-reviewed publications and/or patents)
• Demonstration of good lab practices, with particular attention to safety
• Clear understanding of structural determination using NMR and MS techniques as well as knowledge of related purification methods
• Initial understanding of biological and pharmaceutical principles and working knowledge of structure-based or other computer-aided drug design tools
• Knowledge of the application of parallel synthesis techniques to synthetic or medicinal chemistry

Responsibilities

• Design, synthesize, and purify novel compounds for potential clinical drug development
• Work within Amgen’s Induced Proximity Platform (IPP) using PROTAC modality
• Devise and implement state-of-the-art scientific research through laboratory experiments
• Plan detailed procedures for projects including timelines, milestones, and methodological approaches
• Review, analyze, and interpret scientific data and results
• Provide regular updates, documentation, and communication on project results
• Collaborate with other scientists and keep current with field literature and technology
• Advise supervisors and colleagues, participate in meetings, support publications or patents, and mentor research associates