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University of Southern Denmark

Researcher - Molecular Synthetic Chemistry

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University of Southern Denmark

Odense, DK · Full-time · DKK 400,000 – DKK 500,000

About this role

The Department of Physics, Chemistry and Pharmacy at the University of Southern Denmark collaborates with the Department of Nuclear Medicine, Odense University Hospital. It invites applications from experts in molecular synthetic organic and inorganic chemistry. The position participates in a NovoNordisk Foundation co-funded project available immediately.

The goal is to conjugate cancer targeting peptides to chelators suitable for binding theranostic radioactive isotope pairs for diagnostics and cancer therapy. Research focuses on developing robust synthetic routes to new chelating ligands and their antimony complexes. It includes designing conjugation and cancer cell targeting strategies.

Employ advanced spectroscopic, electrochemical, X-ray diffraction, and fluorescence techniques to investigate structure-reactivity relationships. Collaborate on mechanistic and computational studies and develop protocols for radiolabeling. Conduct electrochemistry and spectroelectrochemistry.

Join a dynamic research environment with state-of-the-art facilities and strong collaborative ties across inorganic, organometallic, bioinorganic chemistry, and nuclear medicine. Supervise undergraduate and graduate students with some undergraduate teaching expected. The 2.5-year position offers possibility for extension.

Requirements

  • Expert in molecular synthetic organic, inorganic chemistry
  • Strong experience in organic synthesis with an emphasis on main group chemistry
  • Solid background in structural and spectroscopic methods of characterization
  • Experience in advanced spectroscopic, electrochemical, X-ray diffraction, and fluorescence techniques
  • Ability to supervise undergraduate and graduate students
  • Capability for some undergraduate teaching

Responsibilities

  • Develop robust synthetic routes to new chelating ligands and in particular their antimony complexes
  • Employ advanced spectroscopic, electrochemical, X-ray diffraction and fluorescence techniques in the investigation of structure–reactivity relationships
  • Design conjugation and cancer cell targeting strategies
  • Collaborate on mechanistic and computational studies
  • Develop protocols for radiolabeling and other studies
  • Conduct electrochemistry and spectroelectrochemistry

Benefits

  • Access to state-of-the-art facilities
  • Dynamic research environment
  • Strong collaborative ties across inorganic, organometallic, bioinorganic chemistry and nuclear medicine
  • 2.5-year position with possibility for extension