
Director, Medicinal Chemistry
18h18 hours agoEnveda
Hyderābād, IN · Full-time · INR 5,000,000 – INR 9,000,000
About this role
Enveda is looking for a Director, Medicinal Chemistry with a demonstrated track record of delivery of optimized leads and clinical candidates for advancing them into human clinical trials. You will lead medicinal chemistry activities for two or more projects in parallel. You will be involved in identifying pre-leads, design and optimization of leads for potency, selectivity and druggability and also strong IP generation.
You will recruit PhD and M.Sc. synthetic chemists and mentor them as medicinal chemists and manage their performance and improve their productivity. You will collaborate with your peers in Medicinal Chemistry and work as a team to increase delivery of compounds to the Clinical Pipeline of Enveda. You will also collaborate with Senior Leaders in other functional departments such as ADME, Analytical Sciences and Pharmacology.
As a member of the broader Drug Discovery team, you will report to the VP, Discovery Chemistry. You get to collaborate on Medicinal Chemistry of Lead Generation and Lead Optimization of Pipeline Projects. Understand Structure Activity Relationships and Structure Property Relationships of various projects.
Collaborate with Medicinal Chemistry, Pharmacology, Analytical, ADME, Tox, IP, Site and Global Leadership. Develop appropriate flow schemes with relevant in vitro, in vivo, ADME/PK and tox studies. Work effectively with Project Management and make presentations of your projects at various Enveda forums.
Requirements
- Doctor of Philosophy in Synthetic Organic Chemistry
- 15-20 years of post-PhD experience in Medicinal Chemistry
- Proven track record of delivery of leads and clinical candidates to the pharmaceutical industry
- Management and mentoring of synthetic chemists
- Good understanding of intellectual property of medicinally valuable compounds with respect to composition of matter, method of use and chemical processes
- Strong understanding of safety practices in organic synthesis laboratories
Responsibilities
- Lead medicinal chemistry activities for two or more projects in parallel
- Identify pre-leads, design and optimization of leads for potency, selectivity, druggability and strong IP generation
- Recruit PhD and M.Sc. synthetic chemists and mentor them as medicinal chemists
- Manage performance and improve productivity of synthetic chemists
- Collaborate with peers in Medicinal Chemistry to increase delivery of compounds to the Clinical Pipeline
- Collaborate with Senior Leaders in ADME, Analytical Sciences and Pharmacology
- Understand Structure Activity Relationships and Structure Property Relationships of various projects
- Develop appropriate flow schemes with relevant in vitro, in vivo, ADME/PK and tox studies
Benefits
- Culture
- Medical
- Block Leaves
- Work-Life Harmony
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