Synthetic Chemist (Oligo) III

The Synthetic Chemist (Oligo) III designs, validates, and implements synthesis projects emphasizing oligonucleotides, peptide and protein bioconjugation, purification, and characterization as therapeutic compound modalities. This role involves performing testing, producing and reporting accurate data. Responsibilities include general lab duties, maintenance, reading standards, setting up tests, monitoring progress, and recording data to validate product efficacy, accuracy, and safety.

Daily tasks include planning, synthesizing, purifying, and analyzing oligonucleotides such as siRNA and PMO, along with bioconjugating them to proteins, peptides, and small molecules. Set up, run, and analyze downstream assays like ELISA and SPR using synthesized compounds. Maintain accurate record keeping, perform independent data analyses, and report findings in written and oral formats.

Work closely with senior scientists to accomplish team objectives and research milestones. Liaise with workgroup team members to plan and track in-vivo experiments, assisting with data analysis. Function independently within a flexible, team-oriented lab environment and cross-functional project teams.

Critically evaluate data, troubleshoot synthesis issues, and contribute intellectually to projects, challenges, solutions, and new methods. Serve as a subject matter expert in oligonucleotides, maintaining up-to-date knowledge of regulations, standards, methods, and protocols. Identify, troubleshoot, and solve escalated technical issues while following client policies and good documentation practices.