About this role
Do you want to be at the cutting edge of innovation that will lead to state-of-the-art therapies for cancer? At AstraZeneca, we turn ideas into life-changing medicines. Our pioneering oncology pipeline enabled by transformative technologies drives us forward, working ambitiously together for patients.
As a Senior Scientist, you will actively contribute to programs in the Oncology Targeted Discovery (OTD) chemistry group. This role deploys expert-level synthetic organic chemistry skills in designing and building complex molecules, both small and non-small, to drive innovation in cancer therapeutics.
Working together with various disciplines across internal and external partners, you will demonstrate a collaborative team player mindset in a fast-paced, multidisciplinary environment. Contribute to delivering highly specific therapeutics including small molecules, peptides and antibody drug conjugates.
Acquire world-class medicinal chemistry skills while supporting a thriving portfolio of future cancer medicines covering a wide range of modalities. Gain a chance to support development and adoption of machine-learning/AI tools and emerging technologies.
Requirements
- Strong organic synthesis background
- Expert-level synthetic organic chemistry skills
- Ability to design and build complex molecules, both small and non-small
- Proficiency in separating, purifying and analyzing chemical matter using validated techniques
- Quantitative and hypothesis-driven approaches to experimentation
- Ability to interpret SAR
- Enthusiasm for deploying machine-learning/AI tools in research
Responsibilities
- Design and execute multi-step modular routes compatible for rapid access to small molecule targets
- Routinely separate, purify and analyze chemical matter, both small and non-small, using validated techniques and protocols
- Employ quantitative and hypothesis-driven approaches to experimentation, including ability to interpret SAR
- Conduct research by deploying machine-learning/AI tools in a seamlessly interactive manner
- Demonstrate a collaborative team player mindset and enthusiasm for multidisciplinary research in a fast-paced environment across various internal/external partners
- Participate in writing and submission of patent applications, peer-reviewed articles, and abstracts for scientific conferences
- Deploy expert-level synthetic organic chemistry skills in designing and building complex molecules
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