Synthetic Chemist I

6d6 days ago

RxSight

Aliso Viejo, US · Temporary · $80,000 – $86,000

About this role

RxSight® is an ophthalmic medical technology corporation headquartered in Aliso Viejo, California that has commercialized the world’s first and only adjustable intraocular lens (IOL) that is customized after cataract surgery. Reporting to the VP of Chemistry R&D, the Synthetic Chemist I plays a key role in the development and optimization of new materials and additives for RxSight’s Light Adjustable Lens. This hands-on position is primarily laboratory-based, involving precise experiment execution, data collection, and analysis.

The role requires synthesizing, purifying, and characterizing novel chromophores, photo-responsive small molecules, and macromolecular additives for polymer resins. Daily tasks include using techniques like HPLC, SEC, GPC, viscosity, rheology, and DSC for purification and analysis of silicone-based polymeric materials. Support for scale-up activities ensures advancement of Light Adjustable Lens technology.

The ideal candidate thrives working independently with strong critical thinking, meticulous record-keeping, and electronic lab notebook experience. They contribute to new processes, protocols, and present findings in chemistry group and project team meetings. No supervisory responsibilities are involved in this position.

This opportunity allows direct contribution to breakthrough solutions that enhance patient outcomes in premium cataract surgery. The self-motivated scientist will provide valuable insights to drive product innovation. Meticulous organization supports uninterrupted research activities.

Requirements

Hands-on experience in the synthesis of small molecules and macromolecules (preferred)
Proficiency with chemical characterization techniques, including UV-Vis, FTIR, NMR, GC, GC-MS, and HPLC
Familiarity with materials characterization techniques such as GPC, DSC, and mechanical property testing using a universal tester
Strong record-keeping skills and experience with electronic lab notebook (ELN) platforms
Ability to work independently while managing multiple tasks with attention to detail and accuracy
Strong critical thinking, problem-solving, and data interpretation skills
Effective written and verbal communication skills for reporting and collaboration

Responsibilities

Synthesize, purify, and characterize novel chromophores and photo-responsive small molecules to advance Light Adjustable Lens technology
Perform purification and analysis using techniques such as HPLC, SEC, and related methodologies
Synthesize and characterize macromolecular additives for polymer resins
Support scale-up activities, including synthesis of building blocks, optimization of reaction parameters, and purification and characterization of intermediates and final products
Conduct basic characterization of silicone-based polymeric materials using GPC, viscosity, rheology, and DSC techniques
Maintain laboratory inventory of chemicals, consumables, and related supplies to ensure uninterrupted research activities
Contribute to the development, documentation, and implementation of new processes and protocols
Present experimental progress, findings, and recommendations during chemistry group and project team meetings